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What is Meiosis? Revision Notes | GCSE Edexcel Higher Biology

Meiosis is a type of cell division that occurs in reproductive organs to produce gametes. Free GCSE Edexcel Biology notes with key definitions and 12 FAQs.

Updated 23 Mar 2026 · Revise Right Team

What is Meiosis? is part of Reproduction in GCSE Edexcel Higher Biology.

4 min

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25

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GCSE Edexcel Higher

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What this lesson covers

Meiosis is a type of cell division that occurs in reproductive organs to produce gametes. Free GCSE Edexcel Biology notes with key definitions and 12 FAQs.

  • Explain what meiosis is and why it's essential for sexual reproduction
  • Describe how meiosis produces four genetically different gametes from one cell
  • Compare the outcomes of meiosis with mitosis in terms of chromosome number
  • Apply knowledge of meiosis to explain genetic variation in offspring

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Key ideas to keep in view

Use this lesson to stay inside Reproduction while connecting the detail back to the wider Topic 3: Genetics topic.

  • Topic 3: Genetics
  • Reproduction
  • GCSE Edexcel Higher Biology

Revision notes

Read the core explanations from What is Meiosis? before testing yourself from memory.

1. Why Do We Need Special Sex Cells?

Your body contains around 37 trillion cells. Nearly all of them have 46 chromosomes - 23 pairs containing all your genetic information. But there's a problem.

If sperm and egg cells also had 46 chromosomes each, a baby would end up with 92 chromosomes. The next generation would have 184. Within a few generations, cells would be drowning in genetic material.

Nature solved this with a clever trick called meiosis - a special type of cell division that cuts the chromosome number in half. This creates gametes (sex cells) with just 23 chromosomes each, so when they fuse, the baby gets exactly 46.

2. What Exactly Is Meiosis?

Think of meiosis as nature's lottery system. It starts with one cell containing two copies of each chromosome (diploid). Through two rounds of division, it produces four gametes, each with just one copy of each chromosome (haploid).

Here's the crucial part: before the cell divides, copies of the genetic information are made. This ensures each gamete gets a complete set of instructions, even though it's only half the usual amount.

But meiosis doesn't just halve the chromosome number - it shuffles the genetic deck. All four gametes end up genetically different from each other and from the parent cell. This genetic mixing is why you look different from your siblings.

3. The Meiosis Process - Two Divisions, Four Outcomes

Meiosis happens in two stages, cleverly called meiosis I and meiosis II. Picture a cell with 4 chromosomes (2 pairs) to keep things simple.

Worked example: Following Chromosomes Through Meiosis

Track what happens to chromosomes as one cell undergoes meiosis

  1. One cell with 4 chromosomes (2 pairs) — This represents the diploid parent cell in reproductive organs
  2. Genetic information is copied before division begins — Each chromosome now consists of two identical copies joined together
  3. Cell divides once → 2 cells, each with 2 chromosomes — Chromosome pairs separate, but each chromosome still has two copies
  4. Both cells divide again → 4 cells, each with 2 chromosomes — The two copies of each chromosome separate

Answer: Four gametes, each with 2 chromosomes (half the original number)

Trap: Many students think meiosis produces two cells like mitosis. Actually, the cell divides twice to form four gametes. The first division separates chromosome pairs, the second separates the copies within each chromosome.

4. Why Are All Gametes Different?

This is where meiosis gets really clever. During the process, chromosomes don't just separate randomly - they get shuffled and mixed up. It's like dealing cards from a deck that's been thoroughly shuffled.

Remember, you have two versions of each chromosome - one from your mum, one from your dad. During meiosis, these chromosomes can end up in any combination in the gametes. Plus, the chromosomes can actually swap pieces with each other, creating entirely new combinations.

This genetic shuffling explains why siblings look different (unless they're identical twins). Each sperm cell your dad produces is genetically unique. Each egg cell your mum produces is genetically unique. When they combine, you get a one-of-a-kind genetic combination.

5. Meiosis vs Mitosis - Spot the Difference

Students often confuse meiosis with mitosis. Both involve cell division, but they serve completely different purposes and have very different outcomes.

Mitosis is for growth and repair. It produces two identical cells with the same chromosome number as the parent. Meiosis is for reproduction. It produces four genetically different gametes with half the chromosome number.

Exam depth extension: In what is meiosis?, connect why do we need special sex cells? to what exactly is meiosis? using clear cause-and-effect statements. When you explain biological processes, include what changes, why it changes, and the consequence for cells, organisms, or populations. If calculations appear, show each step, include units, and end with a sentence that interprets the result in biological context.

6. Exam Technique - Getting Full Marks on Meiosis

Meiosis questions often ask you to compare it with mitosis or explain why genetic variation is important. Here's how to structure your answers for maximum marks.

When explaining genetic variation, link it to survival advantage. Different combinations of genes mean some offspring might be better adapted to environmental changes. This is the raw material for natural selection.

Frequently asked questions

What is meiosis?

Meiosis is a type of cell division that occurs in reproductive organs to produce gametes. One cell divides twice to form four genetically different cells, each with half the chromosome number of the parent cell, so human gametes have 23 chromosomes instead of 46.

What happens in meiosis I and meiosis II?

Before meiosis begins, the genetic information is copied. In meiosis I, the cell divides once and the chromosome pairs separate, giving 2 cells. In meiosis II, both cells divide again and the two copies of each chromosome separate, giving four gametes.

Why is meiosis important?

Meiosis is important because it halves the chromosome number in gametes, so when a sperm and egg fuse the baby gets exactly 46 chromosomes. Without it, a baby would end up with 92 chromosomes. Meiosis also shuffles genes, creating genetic variation.

Where does meiosis take place?

Meiosis takes place in reproductive organs, where it produces gametes (sex cells). It starts with a diploid parent cell and produces four haploid gametes.

How many cells does meiosis produce?

Meiosis produces four genetically different gametes from one cell. Meiosis does not produce two cells like mitosis, because the cell divides twice.

Why are gametes made by meiosis genetically different?

Gametes made by meiosis are genetically different because each parent cell's two versions of every chromosome, one from each parent, can end up in any combination, and chromosomes can swap pieces with each other. This genetic shuffling explains why siblings look different, unless they are identical twins.

How many chromosomes do sperm and egg cells have?

Human sperm and egg cells each have 23 chromosomes, half the 46 found in body cells. When a sperm and an egg fuse, the baby gets exactly 46 chromosomes.

What would happen without meiosis?

Without meiosis, sperm and egg cells would each have 46 chromosomes, so a baby would end up with 92 chromosomes and the next generation 184. Meiosis halves the chromosome number so the number stays the same across generations.

How many divisions are there in meiosis?

Meiosis has two divisions, meiosis I and meiosis II. The first division separates chromosome pairs, and the second division separates the two copies within each chromosome, giving four gametes.

Why is DNA copied before meiosis?

DNA is copied before meiosis so that each gamete gets a complete set of instructions, even though it only has half the usual number of chromosomes. After copying, each chromosome consists of two identical copies joined together.

Why does genetic variation give a survival advantage?

Genetic variation gives a survival advantage because different combinations of genes mean some offspring might be better adapted to environmental changes. This variation, produced by meiosis, is the raw material for natural selection.

Why do siblings look different?

Siblings look different because meiosis shuffles genetic information, so each sperm cell and each egg cell is genetically unique. When they combine, each child gets a one-of-a-kind genetic combination, unless they are identical twins.

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